VU0364289

  • Chemical Properties
CAS No. 1242443-29-3 Cat. No. BCP23956
Name VU0364289
Synonyms VU 0364289;VU-0364289;
Formula C20H21N3O2 M. Wt 335.4
  • Biological Activity
Description VU0364289 is a highly selective mGlu5 positive allosteric modulator (PAM), with an EC50 of 1.6 µM. VU0364289 can reverse amphetamine-induced hyperlocomotion in a dose-dependent manner, which can be used for schizophrenia and other psychiatric research.
Pathways Neuro Signaling Pathway GPCR/G Protein 
Targets mGluR 

Structure

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