BAZ2-ICR

  • Chemical Properties
CAS No. 1665195-94-7 Cat. No. BCP23999
Name BAZ2-ICR
Synonyms BAZ2ICR; BAZ2 ICR;
Formula C20H19N7 M. Wt 357.41
  • Biological Activity
Description BAZ2-ICR is an excellent chemical probe for functional studies of the BAZ2 bromodomains in vitro and in vivo. The bromodomain containing proteins BAZ2A/B play essential roles in chromatin remodeling and regulation of noncoding RNAs. BAZ2-ICR has IC50 (BAZ2A) = 130 nM; IC50(BAZ2B) = 180 nM; logD = 1.05; solubility 25 mM (D2O) and F = 70%.
Pathways Epigenetics 
Targets Epigenetic Reader Domain 

Structure

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