GSK8573
| CAS No. | 1693766-04-9 | Cat. No. | BCP16859 |
| Name | GSK8573 | ||
| Synonyms | GSK-8573;GSK 8573; | ||
| Formula | C20H21NO3 | M. Wt | 323.39 |
| Description | GSK-8573 is the inactive control of GSK-2801.GSK2801 is a A Selective Chemical Probe for BAZ2B/A bromodomains. BAZ2A/B belong to a family of ubiquitously expressed bromodomain containing proteins. Proteins of the BAZ family are characterized by a carboxy-terminal bromodomain adjacent to a PHD finger and a WACZ motif. In addition four other conserved motifs are typically found in the N-terminus of BAZ family members, namely the LH motif (a leucine-rich helical domain), the ZB2 motif and the BAZ 1 and BAZ 2 motifs. Little is known about the biological function of BAZ2B but it has been suggested to regulate nucleosome mobilization by the ATP-dependent chromatin remodeling factor ISWI. | ||
| Pathways | Epigenetics | ||
| Targets | Epigenetic Reader Domain | ||
Structure
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