CTOPA
| CAS No. | 103429-31-8 | Cat. No. | BCP24191 |
| Name | CTOPA | ||
| Synonyms | CTOP;Ctop-NH2;D-PHE-CYS-TYR-D-TRP-ORN-THR-PEN-THR-NH2; | ||
| Formula | C50H67N11O11S2 | M. Wt | 1062.26 |
| Description | CTOP is a potent and selective μ opioid receptor antagonist (Ki values are 0.96 and >10,000 nM for μ and δ receptors respectively). Causes behavioral effects on central administration in vivo. Also increases K+ currents in rat locus ceruleus neurons in vitro via a μ receptor independent mechanism. | ||
| Pathways | Neuro Signaling Pathway Hormone Pathay GPCR/G Protein | ||
| Targets | Opioid Receptor | ||
Structure
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