Dofequidar
| CAS No. | 129716-58-1 | Cat. No. | BCP24839 |
| Name | Dofequidar | ||
| Synonyms | MS-209; MS 209; MS209; | ||
| Formula | C30H31N3O3 | M. Wt | 481.593 |
| Description | Dofequidar, also known as MS-209, is a quinolone-derived sphingomyelin synthase inhibitor that blocks P-glycoprotein and multidrug resistance-associated protein-1, is under development by Schering for the potential treatment of multidrug resistant tumors. Dofequidar was found to sensitizes cancer stem-like side population cells to chemotherapeutic drugs by inhibiting ABCG2/BCRP-mediated drug export. | ||
| Pathways | Ion Channel/Membrane Transporter | ||
| Targets | P glycoprotein | ||
Structure
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