Src Kinase Inhibitor I

  • 化学数据
CAS号 179248-59-0 货号 BCP24909
中文名 Src Kinase Inhibitor I
英文名 Src Kinase Inhibitor I
中文别名
英文别名 Src I1; Src I-1; SrcI1;
分子式 C22H19N3O3 分子量 373.4
  • 用途
生物活性 Src Inhibitor-1 is a member of the class of quinazolines that is quinazoline which is substituted at position 4 by a p-phenoxyanilino group and at positions 6 and 7 by methoxy groups. It is a potent, competitive dual site (both the ATP- and peptide-binding) Src kinase inhibitor. Src Inhibitor-1 is one of the 'gold standards' for Src kinase inhibition that has been shown to use PP1 or PP2 in parallel with Src-I1 to inhbit Src family kinases. It has a role as an EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor. It is a member of quinazolines, a secondary amino compound, an aromatic ether and a polyether.
信号通路 Angiogenesis/Protein Tyrosine Kinase 
靶 点 Src/Bcr Abl 

结构式

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