ISCK03
| CAS No. | 945526-43-2 | Cat. No. | BCP20053 |
| Name | ISCK03 | ||
| Synonyms | ISCK-03;ISCK 03; | ||
| Formula | C19H21N3O2S | M. Wt | 355.45 |
| Description | ISCK03 is a potent c-kit inhibitor. ISCK03 inhibits SCF/c-kit signaling in 501mel human melanoma cells and abolishes melanin production in mice and brownish guinea pigs. ISCK03 also inhibited p44/42 ERK mitogen-activated protein kinase (MAPK) phosphorylation, which is known to be involved in SCF/c-kit downstream signaling. ISCK03 might be used as skin-whitening agents. | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase | ||
| Targets | c Kit | ||
Structure
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