FGF401
| CAS No. | 1708971-55-4 | Cat. No. | BCP25143 |
| Name | FGF401 | ||
| Synonyms | FGF-401; FGF 401; Roblitinib; | ||
| Formula | C25H30N8O4 | M. Wt | 506.56 |
| Description | FGF401 is an inhibitor of human fibroblast growth factor receptor 4 (FGFR4), with potential antineoplastic activity. Upon administration, FGF401 binds to and inhibits the activity of FGFR4, which leads to an inhibition of tumor cell proliferation in FGFR4-overexpressing cells. FGFR4 is a receptor tyrosine kinase upregulated in certain tumor cells and involved in tumor cell proliferation, differentiation, angiogenesis, and survival. | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase | ||
| Targets | FGFR | ||
Structure
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