Siponimod fumarate

  • Chemical Properties
CAS No. 1234627-85-0 Cat. No. BCP25217
Name Siponimod fumarate
Synonyms NVP-BAF-312; NVP-BAF 312; NVP-BAF312; NVP-BAF312-AEA;
Formula C62H74F6N4O10 M. Wt 1149.28
  • Biological Activity
Description Siponimod is a a potent and orally selective S1P Receptor Modulator with EC50 value of 0.39nM for S1P1 receptors and 0.98nM for S1P5 receptors, respectively. Development of sphingosine-1-phosphate receptor 1 (S1P1) modulators to dampen inflammation and its sequelae is becoming increasingly promising for treating medical conditions characterized by significant immunopathology.
Pathways GPCR/G Protein 
Targets S1P Receptor 

Structure

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