Verubecestat TFA salt
| CAS No. | 2095432-65-6 | Cat. No. | BCP26034 |
| Name | Verubecestat TFA salt | ||
| Synonyms | Verubecestat TFA; MK 8931 TFA salt; MK8931 TFA salt; MK-8931 TFA salt;MK-8931; MK 8931; MK8931; MK-8931-009; SCH 900931; SCH-900931; SCH900931; | ||
| Formula | C17H17F2N5O3S.C2HF3O2 | M. Wt | 523.44 |
| Description | Verubecestat, also known as MK-8931 or SCH 900931, is a potent and selective beta-secretase inhibitor, and BACE1 protein inhibitor or Beta-site APP-cleaving enzyme 1 inhibitor. Verubecestat is a promising novel therapeutic drug candidate in Alzheimer's disease. Verubecestat reduced Aβ cerebral spinal fluids (CSF) levels up to 92% and was well tolerated by patients. | ||
| Pathways | Neuro Signaling Pathway | ||
| Targets | Beta secretase | ||
Structure
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