Cintirorgon
| CAS No. | 2055536-64-4 | Cat. No. | BCP28882 |
| Name | Cintirorgon | ||
| Synonyms | LYC 55716;LYC55716; LYC-55716; | ||
| Formula | C27H23F6NO6S | M. Wt | 603.53 |
| Description | Cintirorgon, also known as LYC-55716, is a potent and orally active RORgamma agonist with potential immunomodulatory and antineoplastic activities. LYC-55716 selectively binds to the nuclear receptor transcription factor RORg, forming a receptor complex that translocates to the nucleus, and binds to ROR response elements (ROREs), enhancing the function, proliferation and survival of type 17 T cells, including Th17 (helper T cells) and Tc17 (cytotoxic T cells). | ||
| Related Products | 2055538-47-9（Cintirorgon sodium） | ||
| Pathways | Protease/Metabolic Enzyme | ||
| Targets | ROR | ||
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RORγt agonist enhances anti-PD-1 therapy by promoting monocyte-derived dendritic cells through CXCL10 in cancers
Publications Citing of Biochempartner's Cintirorgon(CAS:2055536-64-4) |
Structure
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