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Cintirorgon Chemical Structure

Cintirorgon

Data Sheet For research use only. Not for human use.
Cat. No. :BCP28882CAS No. :2055536-64-4Purity:98%
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  • Publications Citing of Biochempartner's Cintirorgon
  • Chemical Properties&Biological Activity
CAS No. 2055536-64-4 Cat. No. BCP28882
Related Products 2055538-47-9(Cintirorgon sodium)
Name Cintirorgon
Synonyms LYC 55716;LYC55716; LYC-55716;
SMILES O=C(O)C(C)(C)C[C@H]1CN(S(=O)(C2=CC=CC(C(F)(F)F)=C2)=O)C3=CC(C4=CC(F)=CC(OC(F)F)=C4)=CC=C3O1
Chemical Name
Formula C27H23F6NO6S M. Wt 603.53
Purity 98% Storage Store at 4-8°C
Description Cintirorgon, also known as LYC-55716, is a potent and orally active RORgamma agonist with potential immunomodulatory and antineoplastic activities. LYC-55716 selectively binds to the nuclear receptor transcription factor RORg, forming a receptor complex that translocates to the nucleus, and binds to ROR response elements (ROREs), enhancing the function, proliferation and survival of type 17 T cells, including Th17 (helper T cells) and Tc17 (cytotoxic T cells).
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