Chloroquine diphosphate

CAS No.	50-63-5	Cat. No.	BCP31956
Name	Chloroquine diphosphate
Synonyms	Chloroquine phosphate;Aralen phosphate;7-chloro-4-((4’-diethylamino-1-methylbutyl)amino)quinolinediphosphate;
Formula	C18H32ClN3O8P2	M. Wt	515.86

Description	Chloroquine Phosphate is the phosphate salt of chloroquine, a quinoline compound with antimalarial and anti-inflammatory properties. Chloroquine is the most widely used drug against malaria, except for those cases caused by chloroquine resistant Plasmodium falciparum. Although the mechanism of action is not fully understood, chloroquine is shown to inhibit the parasitic enzyme heme polymerase that converts the toxic heme into non-toxic hemazoin, thereby resulting in the accumulation of toxic heme within the parasite. Chloroquine may also interfere with the biosynthesis of nucleic acids.
Pathways	Microbiology/Virology Others Pathway
Targets	SARS CoV TLR HIV

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