Tegatrabetan
| CAS No. | 1227637-23-1 | Cat. No. | BCP32893 |
| Name | Tegatrabetan | ||
| Synonyms | BC2059; BC-2059; BC 2059;Tegavivint; | ||
| Formula | C28H36N4O6S2 | M. Wt | 588.74 |
| Description | Tegatrabetan is an orally bioavailable and potent β-catenin inhibitor. BC2059 potently induces apoptosis as a single agent and in combination with bortezomib in multiple myeloma. BC2059 induced apoptosis in 10/10 genetically heterogeneous human myeloma cell lines (HMCL) treated with dosages ranging from 50-500nM. | ||
| Pathways | Wnt/Stem Cell | ||
| Targets | Beta catenin | ||
Structure
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