Zamicastat
| CAS No. | 1080028-80-3 | Cat. No. | BCP33811 |
| Name | Zamicastat | ||
| Synonyms | BIA 5-1058; | ||
| Formula | C21H21F2N3OS | M. Wt | 401.48 |
| Description | Zamicastat is a potent and selective dopamine β-mono-oxygenase inhibitor. Zamicastat Prevents the Deterioration of Cardiometabolic and Inflammatory Biomarkers in a Genetic Model of Salt-sensitive Hypertension. Chronic high salt intake deteriorates several cardiometabolic and inflammatory biomarkers in Dahl/SS rats, which can be prevented by dopamine β-hydroxylase inhibition with zamicastat. | ||
| Pathways | Ion Channel/Membrane Transporter | ||
| Targets | P glycoprotein BCRP | ||
Structure
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