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Zamicastat Chemical Structure

Zamicastat

Data Sheet For research use only. Not for human use.
Cat. No. :BCP33811CAS No. :1080028-80-3Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1080028-80-3 Cat. No. BCP33811
Name Zamicastat
Synonyms BIA 5-1058;
SMILES C1C(COC2=C1C=C(C=C2F)F)N3C(=CNC3=S)CCNCC4=CC=CC=C4
Chemical Name
Formula C21H21F2N3OS M. Wt 401.48
Purity 98% Storage Store at 4-8°C
Description Zamicastat is a potent and selective dopamine β-mono-oxygenase inhibitor. Zamicastat Prevents the Deterioration of Cardiometabolic and Inflammatory Biomarkers in a Genetic Model of Salt-sensitive Hypertension. Chronic high salt intake deteriorates several cardiometabolic and inflammatory biomarkers in Dahl/SS rats, which can be prevented by dopamine β-hydroxylase inhibition with zamicastat.
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