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AZD-5672 Chemical Structure

AZD-5672

Data Sheet For research use only. Not for human use.
Cat. No. :BCP48543CAS No. :780750-65-4Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 780750-65-4 Cat. No. BCP48543
Name AZD-5672
Synonyms AZD 5672; AZD5672;
SMILES CCN(C1CCN(CC1)CCC(C2=CC=C(C=C2)S(=O)(=O)C)C3=CC(=CC(=C3)F)F)C(=O)CC4=CC=C(C=C4)S(=O)(=O)C
Chemical Name
Formula C32H38F2N2O5S2 M. Wt 632.78
Purity 98% Storage Store at 4-8°C
Description AZD-5672 is an orally active, potent, and selective CCR5 antagonist (IC50=0.32 nM). AZD-5672 shows moderate activity against the hERG ion channel (binding IC50=7.3 μM). AZD5672 is a substrate of human P-gp, and inhibits P-gp-mediated digoxin transport (IC50=32 μM). AZD-5672 can be used for the research of rheumatoid arthritis.
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