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Dofequidar fumarate Chemical Structure

Dofequidar fumarate

Data Sheet For research use only. Not for human use.
Cat. No. :BCP24840CAS No. :153653-30-6Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 153653-30-6 Cat. No. BCP24840
Name Dofequidar fumarate
Synonyms MS-209; MS 209; MS209;
SMILES
Chemical Name
Formula C34H35N3O7 M. Wt 597.66
Purity 98% Storage Store at 4-8°C
Description Dofequidar fumarate(MS-209 fumarate), an orally active quinoline compound, has been reported to overcome MDR by inhibiting ABCB1/P-gp, ABCC1/MDR-associated protein 1, or both.Dofequidar, also known as MS-209, is a quinolone-derived sphingomyelin synthase inhibitor that blocks P-glycoprotein and multidrug resistance-associated protein-1, is under development by Schering for the potential treatment of multidrug resistant tumors. Dofequidar was found to sensitizes cancer stem-like side population cells to chemotherapeutic drugs by inhibiting ABCG2/BCRP-mediated drug export.
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