Alpelisib hydrochloride
| CAS No. | 1584128-91-5 | Cat. No. | BCP34729 |
| Name | Alpelisib hydrochloride | ||
| Synonyms | BYL-719 HCl;BYL-719 hydrochloride;BYL719 hydrochloride;BYL 719 hydrochloride; | ||
| Formula | C19H23ClF3N5O2S | M. Wt | 477.93 |
| Description | Alpelisib hydrochloride is a potent, orally active, and selective PI3Kα inhibitor with IC50s of 5 nM, 250 nM, 290 nM and 1200 nM for p110α, p110γ, p110δ, and p110β, respectively. Alpelisib hydrochloride (BYL-719 hydrochloride) shows antineoplastic activity. | ||
| Pathways | PI3K/Akt/mTOR | ||
| Targets | PI3K | ||
Structure
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