Vacuolin-1
| CAS No. | 351986-85-1 | Cat. No. | BCP35743 |
| Name | Vacuolin-1 | ||
| Synonyms | Vacuolin 1; Vacuolin1; | ||
| Formula | C26H24IN7O | M. Wt | 577.43 |
| Description | Vacuolin-1 is a potent and cell-permeable lysosomal exocytosis inhibitor. Vacuolin-1 blocks the Ca2+-dependent exocytosis of lysosomes and prevents the release of lysosomal content without affecting the process of resealing. vacuolin‐1 is a potent and selective PIKfyve inhibitor and inhibits late‐stage autophagy by impairing lysosomal maturation. | ||
| Pathways | Others Pathway | ||
| Targets | Autophagy | ||
Structure
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