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Vacuolin-1 Chemical Structure

Vacuolin-1

Data Sheet For research use only. Not for human use.
Cat. No. :BCP35743CAS No. :351986-85-1Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 351986-85-1 Cat. No. BCP35743
Name Vacuolin-1
Synonyms Vacuolin 1; Vacuolin1;
SMILES C1COCCN1C2=NC(=NC(=N2)NN=CC3=CC(=CC=C3)I)N(C4=CC=CC=C4)C5=CC=CC=C5
Chemical Name
Formula C26H24IN7O M. Wt 577.43
Purity 98% Storage Store at 4-8°C
Description Vacuolin-1 is a potent and cell-permeable lysosomal exocytosis inhibitor. Vacuolin-1 blocks the Ca2+-dependent exocytosis of lysosomes and prevents the release of lysosomal content without affecting the process of resealing. vacuolin‐1 is a potent and selective PIKfyve inhibitor and inhibits late‐stage autophagy by impairing lysosomal maturation.
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