
Vacuolin-1 New

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CAS No. | 351986-85-1 | Cat. No. | BCP35743 |
Name | Vacuolin-1 | ||
Synonyms | Vacuolin 1; Vacuolin1; | ||
SMILES | C1COCCN1C2=NC(=NC(=N2)NN=CC3=CC(=CC=C3)I)N(C4=CC=CC=C4)C5=CC=CC=C5 | ||
Chemical Name | |||
Formula | C26H24IN7O | M. Wt | 577.43 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Vacuolin-1 is a potent and cell-permeable lysosomal exocytosis inhibitor. Vacuolin-1 blocks the Ca2+-dependent exocytosis of lysosomes and prevents the release of lysosomal content without affecting the process of resealing. vacuolin‐1 is a potent and selective PIKfyve inhibitor and inhibits late‐stage autophagy by impairing lysosomal maturation. |
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