Apostatin-1 New
Data Sheet
For research use only. Not for human use.
Get Quotation Now* Required Fields.
Please complete the form below and you will get the price list in 1 minute.
* Required Fields.
Please complete the form below and we will contact you shortly.
* Required Fields.
Please complete the form below and we will contact you shortly.
| CAS No. | 2559703-06-7 | Cat. No. | BCP42606 |
| Name | Apostatin-1 | ||
| Synonyms | Apostatin1; Apostatin 1; Apt-1; Apt1; Apt 1; | ||
| SMILES | CN1CCN=C1SC(C2=CC=CC=C2)C(=O)NC3CCCCCC3 | ||
| Chemical Name | |||
| Formula | C19H27N3OS | M. Wt | 345.51 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Apostatin-1 is a novel TRADD inhibitor.Apostatin-1 inhibits RIPK1-dependent apoptosis (RDA) with IC50 of 1.28 μM and shows no significant off-target activity on 97 kinases in KINOME scan profiling.Inhibition of TRADD by Apostatin-1 blocks apoptosis and restores cellular homeostasis by activating autophagy in cells with accumulated mutant tau, α-synuclein, or huntingtin. Treatment with Apt-1 restored proteostasis and inhibited cell death in a mouse model of proteinopathy induced by mutant tau(P301S). | ||
Recommend Products
More >
-
-
Mitophagy activator 1
Cat. No.：BCP49607
No.：2499962-58-0
Product Details -
-
-
-
-
PTC-209 hydrobromide
Cat. No.：BCP47397
No.：1217022-63-3
Product Details -
P62-mediated mitophagy inducer
Cat. No.：BCP47283
No.：1809031-84-2
Product Details -
AGN 196996
Cat. No.：BCP46996
No.：958295-17-5
Product Details -
-
Curcumin analog C1
Cat. No.：BCP42914
No.：39777-61-2
Product Details -
Indophagolin
Cat. No.：BCP41936
No.：1207660-00-1
Product Details -
-
-
-
-
LYN-1604 dihydrochloride
Cat. No.：BCP33963
No.：2310109-38-5
Product Details -
Heparin calcium
Cat. No.：BCP25407
No.：37270-89-6
Product Details -
DL-Selenomethionine
Cat. No.：BCP24111
No.：1464-42-2
Product Details -
Tags:Apostatin-1 supplier,Apostatin-1 purchase,Apostatin-1 manufacturer,Apostatin-1 distributor,Apostatin-1 cost,Apostatin-1 buy,Apostatin-1 for sale