YM-244769 dihydrochloride
| CAS No. | 1780390-65-9 | Cat. No. | BCP40417 |
| Name | YM-244769 dihydrochloride | ||
| Synonyms | YM-244769 2HCl;YM244769 2HCl;YM 244769 2HCl; | ||
| Formula | C26H24Cl2FN3O3 | M. Wt | 516.39 |
| Description | YM-244769 dihydrochloride is an inhibitor of the reverse mode of Na+/Ca2+ exchange (NCX). Potently inhibits Na+-dependent 45Ca2+ uptake (IC50 values are 18, 68 and 96 nM for CCL39 cells transfected with NCX3, NCX1 and NCX2 respectively). Displays selectivity for NCX over other Na+ and Ca2+ transporters. Protects against hypoxia/reoxygenation-induced cell damage in neuronal SH-SY5Y cells expressing NCX1 and NCX3. | ||
| Related Products | 837424-39-2（YM-244769 2HCl） | ||
| Pathways | Ion Channel/Membrane Transporter | ||
Structure
Part data of this page collected from the open network resources, so Biochempartner can not guarantee its accuracy.
For product details of different batches, please contact our Customer
- Service & Tech Support:orders@biochempartner.com
- Website:www.biochempartner.com
Products are for research use only and not for human use. We do not sell to patients.