YKL-5-124

  • Chemical Properties
CAS No. 1957203-01-8 Cat. No. BCP40930
Name YKL-5-124
Synonyms YKL-5124; YKL 5-124; YKL-5 124; YKL5-124;
Formula C28H33N7O3 M. Wt 515.61
  • Biological Activity
Description YKL-5-124 is a potent and highly selective covalent CDK7 inhibitor which causes arrest at the G1/S transition and inhibition of E2F-driven gene expression. This results in no change to RNA polymerase II C-terminal domain phosphorylation.
Pathways Cell Cycle/DNA Damage 
Targets CDK 

Structure

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