I3MT-3

  • Chemical Properties
CAS No. 459420-09-8 Cat. No. BCP40982
Name I3MT-3
Synonyms HMPSNE; HMP SNE; HMP-SNE; I3MT3; I3MT 3;
Formula C17H14N2O2S M. Wt 310.37
  • Biological Activity
Description I3MT-3 is a potent, selective, and cell-membrane permeable inhibitor of 3-Mercaptopyruvate sulfurtransferase (3MST) (IC50=2.7 μM). I3MT-3 is inactive for other H2S/sulfane sulfur-producing enzymes. I3MT-3 targets a persulfurated cysteine residue located in the active site of 3MST.
Pathways Wnt/Stem Cell 

Structure

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