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CAS No. | 459420-09-8 | Cat. No. | BCP40982 |
Name | I3MT-3 | ||
Synonyms | HMPSNE; HMP SNE; HMP-SNE; I3MT3; I3MT 3; | ||
SMILES | CC1=CC(=O)NC(=N1)SCC(=O)C2=CC=CC3=CC=CC=C32 | ||
Chemical Name | |||
Formula | C17H14N2O2S | M. Wt | 310.37 |
Purity | 98% | Storage | Store at 4-8°C |
Description | I3MT-3 is a potent, selective, and cell-membrane permeable inhibitor of 3-Mercaptopyruvate sulfurtransferase (3MST) (IC50=2.7 μM). I3MT-3 is inactive for other H2S/sulfane sulfur-producing enzymes. I3MT-3 targets a persulfurated cysteine residue located in the active site of 3MST. |
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