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TED-347 Chemical Structure

TED-347

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP48533CAS No. ：2378626-29-8Purity：98%
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  • Chemical Properties&Biological Activity
CAS No. 2378626-29-8 Cat. No. BCP48533
Name TED-347
Synonyms TED347; TED 347;
SMILES C1=CC=C(C(=C1)C(=O)CCl)NC2=CC=CC(=C2)C(F)(F)F
Chemical Name
Formula C15H11ClF3NO M. Wt 313.7
Purity 98% Storage Store at 4-8°C
Description TED-347 is an irreversible inhibitor of TEAD4-Yap1 protein-protein interaction (EC50=5.9 uM in FP asssays) via covalent modification of conserved cysteine (Cys367, Ki=1.3 uM), inhibits its binding to Yap1, blocked its transcriptional activity.
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