TED-347
| CAS No. | 2378626-29-8 | Cat. No. | BCP48533 |
| Name | TED-347 | ||
| Synonyms | TED347; TED 347; | ||
| Formula | C15H11ClF3NO | M. Wt | 313.7 |
| Description | TED-347 is an irreversible inhibitor of TEAD4-Yap1 protein-protein interaction (EC50=5.9 uM in FP asssays) via covalent modification of conserved cysteine (Cys367, Ki=1.3 uM), inhibits its binding to Yap1, blocked its transcriptional activity. | ||
| Pathways | Wnt/Stem Cell | ||
Structure
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