MC-VAL-CIT-PAB-CL

  • Chemical Properties
CAS No. 1639351-92-0 Cat. No. BCP42803
Name MC-VAL-CIT-PAB-CL
Synonyms
Formula C28H39ClN6O6 M. Wt 591.1
  • Biological Activity
Description Mc-Val-Cit-PAB-Cl is an ADC linker. Mc-Val-Cit-PAB-Cl can be used to conjugate MMAE and antibody to form antibody-MC-vc-MMAE (e.g., anti-CD22-MC-VC-PABC-MMAE with IC50s of 3.3 and 0.95 nM for BJAB and WSU cell lines in cytotoxicity assay).
Pathways Others Pathway 
Targets ADC Related 

Structure

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