HT-61

  • Chemical Properties
CAS No. 936622-80-9 Cat. No. BCP43676
Name HT-61
Synonyms HT61; HT 61; HY-50A; HY 50A; HY50A;
Formula C26H24N2O M. Wt 380.48
  • Biological Activity
Description HT-61, also known as HY-50A, is a pyrroloquinolone antibiotic potentially for the treatment of staphylococcal infections. HT61 was effective at reducing biofilm viability and was associated with increased expression of cell wall stress and division proteins, confirming its potential as a treatment for S. aureus biofilm infections. HT61 enhances the effect of tobramycin against Pseudomonas aeruginosa in vitro and in vivo.
Pathways Microbiology/Virology 
Targets Antibiotic 

Structure

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