Bomedemstat ditosylate
| CAS No. | 1990504-72-7 | Cat. No. | BCP44102 |
| Name | Bomedemstat ditosylate | ||
| Synonyms | IMG-7289 ditosylate; IMG 7289; IMG7289; | ||
| Formula | C42H50FN7O8S2 | M. Wt | 864.02 |
| Description | Bomedemstat is a lysine-specific histone demethylase 1 (LSD1) inhibitor with antineoplastic activity. Bomedemstat may be useful in the treatment of acute myeloid leukaemia, myelodysplastic syndrome, and Myelofibrosis. IMG-7289 selectively inhibited proliferation and induced apoptosis of JAK2 V617F cells by concomitantly increasing expression and methylation of p53, and, independently, the pro-apoptotic factor PUMA and by decreasing the levels of its antiapoptotic antagonist BCLXL. | ||
| Related Products | 1990504-34-1（Bomedemstat） | ||
| Pathways | Epigenetics | ||
| Targets | Histone Demethylase | ||
Structure
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