Dooku1

  • Chemical Properties
CAS No. 2253744-54-4 Cat. No. BCP44348
Name Dooku1
Synonyms Dooku 1;
Formula C13H9Cl2N3OS M. Wt 326.2
  • Biological Activity
Description Dooku1 is an analog of Yoda1 with antagonist activity against mechanosensitive Piezo1 channel. Dooku1 inhibits 2 μM Yoda1-induced Ca2+-entry with IC50 of 1.3 μM in HEK 293 cells and 1.5 μM in HUVECs, respectively.
Pathways Ion Channel/Membrane Transporter 

Structure

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