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CAS No. | 2253744-54-4 | Cat. No. | BCP44348 |
Name | Dooku1 | ||
Synonyms | Dooku 1; | ||
SMILES | C1=CC(=C(C(=C1)Cl)CSC2=NN=C(O2)C3=CC=CN3)Cl | ||
Chemical Name | |||
Formula | C13H9Cl2N3OS | M. Wt | 326.2 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Dooku1 is an analog of Yoda1 with antagonist activity against mechanosensitive Piezo1 channel. Dooku1 inhibits 2 μM Yoda1-induced Ca2+-entry with IC50 of 1.3 μM in HEK 293 cells and 1.5 μM in HUVECs, respectively. |
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