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Dooku1 Chemical Structure

Dooku1

Data Sheet For research use only. Not for human use.
Cat. No. :BCP44348CAS No. :2253744-54-4Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 2253744-54-4 Cat. No. BCP44348
Name Dooku1
Synonyms Dooku 1;
SMILES C1=CC(=C(C(=C1)Cl)CSC2=NN=C(O2)C3=CC=CN3)Cl
Chemical Name
Formula C13H9Cl2N3OS M. Wt 326.2
Purity 98% Storage Store at 4-8°C
Description Dooku1 is an analog of Yoda1 with antagonist activity against mechanosensitive Piezo1 channel. Dooku1 inhibits 2 μM Yoda1-induced Ca2+-entry with IC50 of 1.3 μM in HEK 293 cells and 1.5 μM in HUVECs, respectively.
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