JQKD-82
| CAS No. | 2410512-38-6 | Cat. No. | BCP44757 |
| Name | JQKD-82 | ||
| Synonyms | JQKD82; JQKD 82; PCK82; PCK-82; PCK 82;JADA82; | ||
| Formula | C27H40N4O5 | M. Wt | 500.64 |
| Description | JQKD82, also known as PCK82, is a cell-permeable and selective KDM5 inhibitor (MM.1S cells, IC50 = 0.42 uM). JQKD82 increases histone H3K4me3 but paradoxically inhibits downstream MYC-driven transcriptional output in vitro and in vivo. JQKD82 is a useful tool compound to block KDM5A function as a potential therapeutic strategy for MM. QKD82 is a more stable ester of KDM5-C49 that is able to deliver the active molecule KDM5-C49 to cells more efficiently | ||
| Pathways | Epigenetics | ||
| Targets | Histone Demethylase | ||
Structure
Part data of this page collected from the open network resources, so Biochempartner can not guarantee its accuracy.
For product details of different batches, please contact our Customer
- Service & Tech Support:orders@biochempartner.com
- Website:www.biochempartner.com
Products are for research use only and not for human use. We do not sell to patients.