布立匹肽
| CAS号 | 1445179-97-4 | 货号 | BCP46470 |
| 中文名 | 布立匹肽 | ||
| 英文名 | Brimapitide | ||
| 中文别名 | |||
| 英文别名 | D-JNKI-1;L-JNKi1; | ||
| 分子式 | C164H286N66O40 | 分子量 | 3822.4 |
| 生物活性 | Brimapitide is a protease resistant, potent inhibitor specific for JNK (JNK1, JNK2 and JNK3). L-JNKi 1 does not directly affect kinase activity e.g. by competing with the ATP-binding site of the protein kinase, rather L-JNKi1 inhibits the interaction between JNK and its substrate, resulting in a JNK K.O. phenotype. In contrast to pure diffusion they are actively transported into cells, where they remain until their proteolytic degradation. The c-Jun N-terminal kinases (JNK1, 2, 3), members of the mitogen-activated protein kinase (MAPK) superfamily, are activated by a wide variety of extracellular stimuli such as inflammatory cytokines, heat shock and ischemia. | ||
| 信号通路 | MAPK Pathway | ||
| 靶 点 | JNK | ||
结构式
本页面部分数据来自于公开的网络资源,所以瀚香生物不能保证其准确性。
不同批次的产品详情请咨询我们的客服：
- 全国免费电话：400-099-8200
- 在线客服:
瀚香生物（Biochempartner) 的所有产品和服务仅用于科学研究，禁止用于人体和治疗！