Pavinetant
| CAS号 | 941690-55-7 | 货号 | BCP48976 |
| 中文名 | Pavinetant | ||
| 英文名 | Pavinetant | ||
| 中文别名 | |||
| 英文别名 | AZD-2624; AZD2624; AZD 2624; MLE-4901; MLE4901; MLE 4901; AZD-4901; AZD 4901; AZD4901; AZ-12472520; AZ 12472520; AZ12472520; | ||
| 分子式 | C26H25N3O3S | 分子量 | 459.56 |
| 生物活性 | Pavinetant is a small-molecule, orally active, selective neurokinin-3 (NK3) receptor antagonist which is under development by AstraZeneca and Millendo Therapeutics for the treatment of hot flashes and polycystic ovary syndrome (PCOS). It was also under investigation for the treatment of schizophrenia, but development was discontinued for this indication due to lack of effectiveness. As of 2017, the drug is in phase II clinical trials for hot flashes and PCOS. | ||
| 信号通路 | Neuro Signaling Pathway GPCR/G Protein | ||
| 靶 点 | NK Receptor | ||
结构式
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