SGI-7079
| CAS No. | 1239875-86-5 | Cat. No. | BCP21014 |
| Name | SGI-7079 | ||
| Synonyms | SGI 7079; SGI707; | ||
| Formula | C26H26FN7 | M. Wt | 455.54 |
| Description | SGI-7079 is a potent and selective Axl inhibitor with potential anticancer activity. SGI-7079 effectively inhibited Axl activation in the presence of exogenous Gas6 ligand. SGI-7079 inhibited tumor growth in a dose dependent manner. Axl is a potential therapeutic target for overcoming EGFR inhibitor resistance. | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase | ||
| Targets | TAM Receptor | ||
Structure
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