盐酸多巴胺
| CAS号 | 62-31-7 | 货号 | BCP06611 |
| 中文名 | 盐酸多巴胺 | ||
| 英文名 | Dopamine hydrochloride | ||
| 中文别名 | 多巴胺盐酸盐;去甲肾上腺素EP杂质C盐酸盐; | ||
| 英文别名 | Dopamine HCl;Inotropin;Intropin;ASL279;ASL 279;ASL-279;3,4-dihydroxyphenethylamine; | ||
| 分子式 | C8H12ClNO2 | 分子量 | 189.64 |
| 生物活性 | Dopamine Hydrochloride is the hydrochloride salt form of dopamine, a monoamine compound with positive inotropic activity. Dopamine is a naturally occurring catecholamine formed by decarboxylation of dehydroxyphenylalanine and a precursor of norepinephrine and epinephrine. Dopamine binds to alpha-1- and beta-1- adrenergic receptors. Mediated through myocardial beta-1-adrenergic receptors, dopamine increase heart rate and force, thereby increasing cardiac output. Alpha-1-adrenergic receptor stimulation on vascular smooth muscle, leads to vasoconstriction and results in an increase in systemic vascular resistance. Stimulation of dopaminergic receptors in renal vasculature, leads to renal blood vessel dilation, and an increase in glomerular filtration rate, renal blood flow, sodium excretion, and urine output. | ||
| 信号通路 | Neuro Signaling Pathway GPCR/G Protein | ||
| 靶 点 | Dopamine Receptor | ||
结构式
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