Moexipril hydrochloride

CAS No.	82586-52-5	Cat. No.	BCP21379
Name	Moexipril hydrochloride
Synonyms	Moexipril HCL; RS 10085; RS-10085; RS10085; SPM-925; SPM 925; SPM925; CI-925; CI 925; CI925;
Formula	C27H35ClN2O7	M. Wt	535.03

Description	Moexipril Hydrochloride is the hydrochloride salt form of moexipril, a prodrug and non-sulfhydryl angiotensin converting enzyme (ACE) inhibitor with antihypertensive activity. Moexipril hydrochloride is hydrolized into its active form moexiprilat, which competitively inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This prevents the actions of the potent vasoconstrictor angiotensin II and leads to vasodilatation. It also prevents angiotensin II-induced aldosterone secretion by the adrenal cortex, thereby promoting diuresis and natriuresis. Moexipril hydrochloride also directly suppresses renin release.
Pathways	Protease/Metabolic Enzyme Hormone Pathay
Targets	RAAS/ACE

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