SB505124

  • Chemical Properties
CAS No. 694433-59-5 Cat. No. BCP22718
Name SB505124
Synonyms SB-505124;SB 505124;
Formula C20H21N3O2 M. Wt 335.4
  • Biological Activity
Description SB-505124 is a selective inhibitor of TGFβR with IC50 of 129 nM and 47 nM for ALK4, ALK5, respectively, and it does not inhibits ALK1, 2, 3, or 6 but ALK7.
Pathways TGF beta/Smad  Wnt/Stem Cell 
Targets BMP/TGF beta Receptor TGF β/Smad 

Structure

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