甲磺酸联苯芦诺
| CAS号 | 350992-13-1 | 货号 | BCP02133 |
| 中文名 | 甲磺酸联苯芦诺 | ||
| 英文名 | Bifeprunox mesylate | ||
| 中文别名 | |||
| 英文别名 | DU-127090;DU 127090;DU127090; | ||
| 分子式 | C24H23N3O2.CH4O3S | 分子量 | 481.57 |
| 生物活性 | Active as an antipsychotic compound through activation of the serotonin 5-hydroxytryptamine (5-HT)1A receptor.Bifeprunox, also known as DU-127090, is a partial dopamine and serotonin agonist potentially for the treatment of schizophrenia. Bifeprunox influences nicotine-seeking behaviour in response to drug-associated stimuli in rats. Bifeprunox suppresses in vivo VTA dopaminergic neuronal activity via D2 and not D3 dopamine autoreceptor activation. | ||
| 信号通路 | Neuro Signaling Pathway GPCR/G Protein | ||
| 靶 点 | 5 HT Receptor/Serotonin Receptor Dopamine Transporter Dopamine Receptor | ||
结构式
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