NSC-348884
| CAS No. | 81624-55-7 | Cat. No. | BCP09001 |
| Name | NSC-348884 | ||
| Synonyms | NSC 348884; NSC348884; | ||
| Formula | C38H40N10 | M. Wt | 636.79 |
| Description | NSC348884 is a nucleolar phosphoprotein that displays several biological activities in ribosome biogenesis, cell proliferation, cytoplasmic/nuclear shuttle transportation, nucleic acid binding, ribonucleic cleavage, and centrosome duplication. NSC 348884 is a putative inhibitor of nucleophosmin (NPM). NSC 348884 inhibits NPM oligomer formation, up-regulates p53 and induces apoptosis. | ||
| Pathways | Apoptosis Pathway | ||
| Targets | Apoptosis Inducer p53 | ||
Structure
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