PPQ-102
| CAS No. | 931706-15-9 | Cat. No. | BCP09625 |
| Name | PPQ-102 | ||
| Synonyms | PPQ102; PPQ 102; | ||
| Formula | C26H22N4O3 | M. Wt | 438.48 |
| Description | CFTR Inhibitor IV, PPQ-102 is a compound that targets intracellular nucleotide binding domain(s) of CFTR and inhibits CFTR- mediated chloride current in a voltage-dependent and reversible manner. CFTR Inhibitor IV, PPQ-102 is a cell-permeable pyrimido-pyrrolo-quinoxalinedione (PPQ) and in studies has shown that the nature of PPQ-102 inhibition is due to a stabilization of the channels in a closed state. | ||
| Pathways | Ion Channel/Membrane Transporter | ||
| Targets | CFTR | ||
Structure
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