SB-265610
CAS No. | 211096-49-0 | Cat. No. | BCP28242 |
Name | SB-265610 | ||
Synonyms | SB 265610; SB265610; | ||
Formula | C14H9BrN6O | M. Wt | 357.17 |
Description | SB-265610 is a potent CXCR2 antagonist that inhibits CINC-1-mediated but not C5a-mediated Ca2+ mobilization (IC50 values are 3.4 and 6800 nM respectively). It inhibits CINC-induced chemotaxis and attenuates neutrophil accumulation in inflammatory lung injury in vivo. | ||
Pathways | GPCR/G Protein | ||
Targets | CXCR |
Structure
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