Delapril hydrochloride

  • Chemical Properties
CAS No. 83435-67-0 Cat. No. BCP14202
Name Delapril hydrochloride
Synonyms Delapril HCl;CV-3317;CV 3317;CV3317;
Formula C26H32N2O5.HCl M. Wt 489.01
  • Biological Activity
Description Delapril Hydrochloride is the hydrochloride salt of delapril, a lipophilic, non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. As a prodrug, delapril is converted to two active metabolites, delapril diacid and 5-hydroxy delapril diacid, which competitively bind to and inhibit ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This prevents the potent vasoconstrictive actions of angiotensin II and results in vasodilation. Delapril also decreases angiotensin II-induced aldosterone secretion by the adrenal cortex, which leads to an increase in sodium excretion and subsequently increases water outflow.
Pathways Protease/Metabolic Enzyme Hormone Pathay 
Targets RAAS/ACE 

Structure

Part data of this page collected from the open network resources, so Biochempartner can not guarantee its accuracy.
For product details of different batches, please contact our Customer
Service & Tech Support:orders@biochempartner.com
Website:www.biochempartner.com
Products are for research use only and not for human use. We do not sell to patients.