BAL27862
| CAS No. | 798577-91-0 | Cat. No. | BCP16476 |
| Name | BAL27862 | ||
| Synonyms | BAL-27862;BAL 27862; | ||
| Formula | C20H17N7O2 | M. Wt | 387.39 |
| Description | BAL27862 is a a novel synthetic potent inhibitor of tubulin polymerization that induces cancer cell death. BAL27862 is a novel microtubule-destabilizing drug that is currently undergoing phase I clinical evaluation as the prodrug BAL101553. BAL27862 elicits a unique microtubule (MT) phenotype, distinct from paclitaxel, vinblastine and colchicine, has broad in vitro anti-proliferative activity against a diverse range of human tumor lines (low nM IC50s) and induces significant antitumor responses in a range | ||
| Pathways | Ion Channel/Membrane Transporter Neuro Signaling Pathway | ||
| Targets | P glycoprotein | ||
Structure
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