BIBS 39
| CAS No. | 133085-33-3 | Cat. No. | BCP17735 |
| Name | BIBS 39 | ||
| Synonyms | BIBS-39;BIBS39; | ||
| Formula | C31H34N4O3 | M. Wt | 510.635 |
| Description | BIBS-39 is a novel, nonpeptide angiotensin II receptor antagonist, showing antihypertensive activity. In contrast to the angiotensin II receptor subtype 1 (AT1) selective drug DuP 753, BIBS-39 also displays affinity for the angiotensin II receptor subtype 2. BIBS 39 displaced [125I] AII from its specific binding sites with a K(i) value of 29 +/- 7 nM for the AII subtype I (AT1) receptor and a K(i) value of 480 +/- 110 nM for the AII subtype 2 (AT2) receptor. BIBS 39 appears to be effective antihypertensives in the model of the renal hypertensive rat. | ||
| Pathways | GPCR/G Protein | ||
| Targets | Angiotensin Receptor | ||
Structure
Part data of this page collected from the open network resources, so Biochempartner can not guarantee its accuracy.
For product details of different batches, please contact our Customer
- Service & Tech Support:orders@biochempartner.com
- Website:www.biochempartner.com
Products are for research use only and not for human use. We do not sell to patients.