Halofuginone Hydrochloride

  • Chemical Properties
CAS No. 1217623-74-9 Cat. No. BCP19375
Name Halofuginone Hydrochloride
Synonyms
Formula C16H18BrCl2N3O3 M. Wt 451.14
  • Biological Activity
Description Halofuginone is the competitively inhibitor of prolyl-tRNA synthetase with Ki of 18.3 nM.It could also down-regulate Smad3 and blocked TGF-β signaling at 10 ng/ml in mammal.
Pathways TGF beta/Smad  Wnt/Stem Cell 
Targets TGF β/Smad 

Structure

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