Etalocib

  • Chemical Properties
CAS No. 161172-51-6 Cat. No. BCP29555
Name Etalocib
Synonyms VML295; VML-295; VML 295; LY293111; LY-293111; LY 293111; PDSP1001237; PDSP2001221;
Formula C33H33FO6 M. Wt 544.61
  • Biological Activity
Description Etalocib, also known as LY293111 and VML295, is a novel diaryl ether carboxylic acid derivative, is a potent and selective inhibitor of the lipoxygenase pathway either directly through 5'-lipoxygenase or via antagonism of the leukotriene B4 (LTB4) receptor. LY293111 has antineoplastic activity in a variety of preclinical models.
Pathways Protease/Metabolic Enzyme GPCR/G Protein 
Targets Leukotriene Receptor Lipoxygenase 

Structure

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