LIT-927
| CAS No. | 2172879-52-4 | Cat. No. | BCP29866 |
| Name | LIT-927 | ||
| Synonyms | LIT 927; LIT927; | ||
| Formula | C17H13ClN2O3 | M. Wt | 328.75 |
| Description | LIT-927 is a Locally and Orally Active CXCL12 Neutraligand with Anti-inflammatory Effect in a Murine Model of Allergic Airway Hypereosinophilia. displays a higher solubility. LIT-927 reduces eosinophil recruitment in a murine model of allergic airway hypereosinophilia. Combined with a high binding selectivity for CXCL12 over other chemokines, LIT-927 represents a powerful pharmacological tool to investigate CXCL12 physiology in vivo, and to explore the activity of chemokine neutralization in inflammatory and related diseases. | ||
| Pathways | GPCR/G Protein | ||
| Targets | CXCR | ||
Structure
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